Abstract Background More than 90% of heart murmurs in children are innocent.Frequently the skills of the first examiner are not adequate to differentiate between innocent and pathological murmurs.Our goal was to Color Blender evaluate the value of a simple and low-cost phonocardiographic recording and analysis system in determining the characterist
ABSTRACT RNA viruses replicate as complex mutant spectra termed viral quasispecies.The frequency of each individual genome in a mutant spectrum depends on its rate of generation and its relative fitness in the replicating population ensemble.The advent of deep sequencing methodologies allows for the first-time quantification of haplotype abundances
In indeterminate alfalfa nodules, the establishment of the senescent zone IV, in which both symbionts undergo simultaneous degeneration, has been considered, until now, as the end point of the symbiotic interaction.However, we now describe an additional zone, zone V, proximal to the senescent zone IV and present in alfalfa nodules more than 6 weeks
BACKGROUND:Although the generic drug approval process has a long-term successful track record, concerns remain for approval of narrow therapeutic index generic immunosuppressants, such as tacrolimus, in transplant recipients.Several professional transplant societies and publications have generated skepticism of the generic approval process.Three ma
Management of social-ecological systems takes place amidst complex governance processes and cross-scale institutional arrangements that are mediated through politics of scale.Each management scenario generates distinct cross-scale trade-offs in the distribution of pluralistic values.This study explores the hypothesis that conservation-oriented mana